The pitcher that struck out the most batters in history is Nolan Ryan. He has struck out 5,714 batters during his career from September 11, 1966 until September 22, 1993.
Nolan Ryan had 5,714 career strikeouts.
Well in more recent times as of post-1900s, Nolan Ryan struck out 383 batters in 1973 season with the California Angels. Hope that helps.
I believe you mean How many people did Nolan Ryan "strike out". And he "struck out" 5,714 people.
In the 2011 season, he has 147 strikeouts. In his career, he has struck out 1,861 batters