It is for sure possible to do so, it is just not effective for everyone. There have been multiple successful quarterbacks in NFL history that have worn gloves on their throwing hand, Kurt Warner is one for example. It can effect ones ability as far as accuracy and spiral are concerned because of the grip on the ball. On the other hand it can be very efficient for someone who doesn't have very big hands because it will help you move around in the backfield with the ball in your hand without worrying about fumbling.
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