Peyton Manning played for the Colts from 1998-2005, setting a single-season record of 49 touchdown passes in 2004.
he holds the ny giants record of 36 tds in a single season
Sonny Jurgensen - 31 in 1967.
Tom Brady (New England Patriots) 2006-2007 Season. 50 touchdown passes in the regular season.
Through the 2009 season, Y.A. Tittle with 36 TD passes in 1963.
In the NFL, Patriots quarterback Tom Brady holds the record for the most passing touchdowns in a single season, with 50 touchdown passes in 2007. In NCAA college football, Brett Elliott of Linfield College (Division III) holds the single season passing touchdown record, with 61 in 2004. The NCAA Division I record is held by Colt Brennan of the University of Hawaii at Manoa, with 58 touchdown passes in 2006. Steve Grogan of the 1976 New England Patriots scored the most rushing touchdowns by a quarterback in NFL history with 12.
He broke it Week 17 against the New York Giants, it was to Randy Moss, who got his 23rd touchdown that season breaking single season receiving touchdowns in a single season record.
He broke Dan Marinos record in 2004 with 49 tds only to have the record broken by tom brady in 2007 with 50