The Lions' record on Thanksgiving Day is 33-36-2.
Since 1980 the Detroit Lions have won 14 games on Thanksgiving.
From the Detroit Lions website: The Lions have played the Packers the most of any franchise on Thanksgiving with 16 meetings between the two teams. Detroit and Chicago have battled a total of 15 times. The Lions have played 21 different NFL teams on Thanksgiving Day.
The two teams have never played on Thanksgiving because they traditionally host games on the holiday. In 2010, the Cowboys defeated the Lions at Cowboys Stadium, 35-19, on the Sunday before Thanksgiving.
Its a tradition started by the first Detroit Lions owner G.A. Richardson who in an attempt to boost attendence to Lions games set up the first Thanksgiving day game in 1934. The Lions played the undefeated Chicago Bears to a very close loss 16-19 but so many people listened on the radio and full crowd at the game made history as a classic was born and the Lions have played Thanksgiving day ever since.
The answer is 59.