The first NFL game was in 1920, although the league was then named the "American Professional Football Association". It would be renamed the NFL in 1922.
NFL use red.
No. Not in the NFL, only in college football
Only if it relates to a first down or touchdown.
September 15th 2010 is the first nfl game
The first college football game was played in 1869 between Rutgers and Princeton. The first NFL game was played in 1920 between Dayton and Columbus.