I'm not aware of any lefties who have played these positions regularly, but there have been situations where left-handers played them in emergency situations. Don Mattingly had to substitute at third base for the Yankees in the late 80's when their regular third baseman was hurt. Mike Squires (who like Mattingly, usually played first base) caught for the White Sox once in the early 80's.
For the 2009 season, that is Philadelphia Phillies left handed pitcher Jamie Moyer and Atlanta Braves left handed pitcher Tom Glavine. Each will be playing their 23rd MLB season.
There is no rule allowing or disallowing the act, therefore it is legal. As a matter of fact, jumping over the catcher might be in compliance with rules requiring runners to avoid contact with a defensive player. *Some leagues have "Must Slide" rules at home to eliminate colisions, so be familiar with your local leagues
Philip Hughes, right handed pitcher for the New York Yankees who pitched earlier in the season but is currently on the disabled list, will turn 21 on June 24.
Yes; she's a left handed player.
Generally the designated runner is to be used for the catcher when there are two outs, sometimes the number of outs is not important. The PURPOSE of the rule is to allow the catcher to put his equipment on sooner and speed up the game. Some leagues use the designated runner for both the pitchers and catchers. This allows the pitcher and catcher to also rest. In addition it gives a player the opportunity to participate who is not in the line-up.
antione mkylos is the record shortest player in the history of MLB