You can play 2 players on NFS Hot pursuit by online play.
4 players can play in Left 4 Dead 2.
Up to four players can play on the Sims 2 for Gamecube.
Up to two players can play Borderlands 2 on the same system.
In all systums, you can play with up to 2 players
Gundam crossfire can play 1-2 players but if you play with 2 players you will have to fight each other
If 10 players play 1 game then 20 players play 2 games
Yes 2 players can play NBA 2k11 on a xbox.
yes you can play binweevils on the wii 2 players and 3 players
You can play two players on halo 3 with two controllers
There is only one game on the Wii Fit that alows you to play with 2 players and that is a 2 player run.